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KMID : 0357919760100010137
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Korean Journal of Pathology
1976 Volume.10 No. 1 p.137 ~ p.142
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Bacterial and Fungal Species Isolated from Cerebrospinal Fluid in the Past Five Years
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Abstract
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Because of the significant mortality rate and sometimes serious neurological sequelae,
pyogenic bacterial meningitis continues to be a serious infection despite of the availabil-
ity of effective antibiotics. Laboratory diagnosis, on the basis of bacteriological study in
particular, is an essential procedure not only for the determination of etiology but also
for the selection of proper antibiotics.
An analysis of the bacterial and fungal isolations during the years 1970-74 at Yonsei
University Medical Center was made to draw the following summaries.
1. Fifty three bacteria and one fungus strains were isolated : of which 60.1% were S.
pneumoniae, N. meningitidis and H. influenzae. Isolates include one strain each of B.
alvei and C. neoformans.
2. Culture positive patients were most frequently those who belonged to an age group
of 1month-1 year.
3. H. influenzae was isolated from Patients upto 2-4 year old group and N. mening-
itidis upto 20-29 year old group, while S. pneumoniae was isolated from young and
from old groups
4. Male to female ratio of culture positive patient was approximately 2 : 1.
5. N. meningitidis was isolated from winter to early summer months and S. pneumo-
niae and H. influenzae from autumn to spring months.
6. Some of the patients from whom opportunistic pathogens were isolated had injuries
or operations on their heads. Some had bacterial infections on other part of their bodies.
7. Few isolates of N. meningitidis, S. pneumoniae and H. influenzae showed in vitro
resistance to some of the tested antibiotics.
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